Bohee Lee

Responsiveness to oral corticosteroids in recurrent wheeze of early childhood

Wheezing is mainly caused by asthma in childhood and around one-third of pre-schoolers experience at least one wheezing episode in childhood. Recurrent wheezing is the most common clinical disorder amongst infants and pre-school aged children. Wheezing can last instantly but many children are suffering from recurrent wheezing throughout their childhood. Therefore, it is not deniable that this disorder causes a substantial impact on the affected children’s quality of life and their parent as well as a whole society. 

Oral corticosteroids (OCS) is generally used to relieve wheezing in young children. Many studies in older children have proved positive results in terms of medication burden and hospitalisation. However, studies for responsiveness on OCS in young children have shown inconsistent results. Regarding the early prediction of responsiveness on OCS, some algorithms have been proposed, but there is a need for developing algorithms reducing great heterogeneity of mechanisms, reflecting multiple risk factors and increasing reliability with enough confidence.

About me

I have completed MSc Clinical Pharmacy at Dankook University in South Korea and MPH at University of Edinburgh. My research interests lie in the management of asthma or recurrent wheezing including issues around responsiveness to a medicine in a certain age group and use of the medicine.

Publications

1. Lee, B., & Lee, Y. (2019). Evaluation of medication use and pharmacy services for visually impaired persons: Perspectives from both visually impaired and community pharmacists. Disability and Health Journal, 12(1), 79-86. doi: 10.1016/j.dhjo.2018.07.012
2. Lee, Y., Kim, H., Choi, J., Lee, B., & Lee, S. (2018). Evaluation of pharmacokinetic, pharmacodynamic, efficacy, and safety data of low-dose ticagrelor versus standard-dose in East Asians: a systematic review. Therapeutics And Clinical Risk Management, Volume 14, 83-93. doi: 10.2147/tcrm.s152276
3. Kim, J., Kim, M., Lee, B., Kim, J., Ahn, E., & Ko, H. et al. (2016). Marmesin-mediated suppression of VEGF/VEGFR and integrin β1 expression: Its implication in non-small cell lung cancer cell responses and tumour angiogenesis. Oncology Reports, 37(1), 91-97. doi: 10.3892/or.2016.5245

Research activity

1.  “Korean women’s awareness, psychological attitude, and knowledge on oral contraceptive use”. Korea Academy of Community Pharmacy, Seoul, South Korea. (Poster presentation- Nov.2017)
2. “Evaluation of medication counseling on oral contraceptives at community pharmacies in Korea: a mystery shopper study”. The Korea Academy of Community Pharmacy, Seoul, South Korea. (Poster presentation. Nov.2017)
3. “Investigation on the status of medication usage and adherence in visually impaired and suggestion for improvement” . The 77th FIP World Congress of Pharmacy and Pharmaceutical Sciences 2017 Seoul, South Korea. (Poster presentation. Sep.2017)
4. “Evaluation of efficacy and safety of ticagrelor compared to clopidogrel in East Asian patients with acute coronary syndrome: a systemic review and meta-analysis”.The International Convention of the Pharmaceutical Society of Korea, Seoul, South Korea.(Poster presenation. Sep.2016)
5. “Analysis of the characteristics and career aims of Korean international students in the US PharmD program”. The 16th Asian Conference on Clinical Pharmacy, Seoul, South Korea(poster presentation. July.2016)